Patients who suffer from mental disorders, have cognitive impairment and problems with blood circulation in the brain, are prescribed various types of nootropics. Due to the presence of nicotinoyl gamma-aminobutyric acid, the medical drug Picamilon is particularly effective in the treatment of neuroses of varying severity, as well as in restoring cerebral circulation in the process of increasing efficiency and restoring mental activity.

Active component and existing form

The main component contained in the drug, regardless of the form of release, is nicotinoyl-gamma-aminobutyric acid (nicotinoyl GABA). The drug is produced in the form of an injection solution placed in a fully closed ampoule container. The number of ampoules in the package - 10 pcs. The volume of each container is 2 ml with different dosage parameters:

50 mg / ml, which corresponds to a 5% concentration of the active substance;
100 mg / ml, or 10% concentration of the active ingredient.

Based on the existing types of dosage for injection, the solution symbols are used - "Pikamilon 50" and "Pikamilon 100", respectively.

Along with the liquid for injections, drugs are also available in the form of tablets with a dosage size of 20 and 50 mg of the contained nicotinoyl-gamma-aminobutyric acid. In this case, sucrose, starch, calcium stearate and some other components are used as auxiliary substances. No additional substances are added to the solution intended for injection.

Scope and effect

For patients who are prescribed Picamilon injections, the instructions for use must be observed without fail. Moreover, the reception can be started only on the recommendation of the attending physician. The drug has such an effect on the state of the patient's body:

nootropic;
antiaggregatory;
antioxidant.

The patient experiences a positive tranquilizing and psychostimulating effect. Thanks to the action of the active component, metabolism in brain tissues is normalized and blood flow improves. At the same time, people taking the drug experience effects of this kind:

minimization of headaches and manifestations of migraine;
memory activation;
increased physical and mental activity;
sleep recovery;
reduction of nervousness and increased anxiety;
positive influence in the process of restoring motor and speech functions;
reducing the negative effect of ethanol on the central nervous system
activation of blood flow in the region of the retina and optic nerve.

Absorption of substances occurs in full. This process is quite fast. Penetration into the body goes through the BBB, and then there is a long-term retention of the components in the tissues with a bioavailability of 50-88%. Excretion is carried out in the same form without changes through the kidneys. The half-life with urine is about an hour.

Terms of appointment and contraindications

The medical preparation Picamilon in the form of an injection solution is prescribed as an independent drug, as well as to provide auxiliary support in complex therapy.

When is it appropriate and necessary?

The main ailments and types of conditions for which the remedy is prescribed are:

ischemic stroke, not aggravated by a severe course of the disease, subacute condition of the patient, as well as recovery after a stroke;
manifestations of insufficiency of blood circulation processes in the brain;
encephalopathy of discircular type;
autonomic dysfunction;
neuro-type infections, in particular encephalitis or neurosyphilis;
transferred injuries of a craniocerebral nature;
susceptibility to attacks of anxiety or fear, nervousness, irritability, mood swings, depressive manifestations;
psychoses of senile manifestation;
asthenia due to nervous overload or physical overstrain;
encephalopathy of alcoholic origin, chronic alcohol dependence, complex treatment of the state of intoxication;
maintenance therapy during the rehabilitation period after the cure for ailments;
prevention of migraine and interruption of the pain syndrome;
open-angle glaucoma at the primary stage in the absence of disturbances in the level of intraocular pressure;
problems with the retina and disorders in the work of the optic nerve;
adaptive effect on the work of the bladder in violation of the processes of urination;
complex activation of the body's resistance to increased loads, restoration of the state after them.

Features of reception in difficult situations

Picamilon, as a rule, is prescribed to children aged 3 years and older. Injections can be used in a serious condition of the patient:

in case of violations in the blood supply system of the brain tissues of a severe stage;
in conditions of increased irritability and neuroses that occur against the background of autonomic dysfunctions, for example, excessive sweating, heart palpitations, breathing problems.

In special situations, it is also possible to prescribe to babies under 3 years of age with serious sleep disorders or behavioral anomalies. Such a decision is made only when the risks from the disease exceed the possible negative impact on the body. But in most cases, it is advisable to abandon early use.

Important. Do not use a drug to stimulate intellectual development.

The medicinal product Picamilon is also used in the treatment of children who have problems with urination. As a rule, tablets are used, and the dose is adjusted by the attending physician on an individual basis.

Despite the fact that no cases of influence on the process of driving a car have been identified, it is not recommended to combine the use of the drug with the performance of work that requires special attention. The simultaneous use of alcohol is also prohibited. Do not use in patients who have been diagnosed with impaired liver and kidney function in a chronic form.

When taken together with barbiturates, one should take into account the increase in their metabolism with more active excretion from the body. Narcotic-type analgesics with such a combined appointment are characterized by a great effect.

Contraindications

The drug in injections and injections intended for administration through a vein, as well as in tablet form, is not used in a situation of personal hypersensitivity to constituent substances, as well as in renal or hepatic pathological changes.

It is unacceptable to prescribe to persons in whom diagnosed changes in cerebral circulation are in an acute stage. The drug is also contraindicated for women during pregnancy and lactation.

Taking the drug: dosages and problems

Most experts agree that the preferred option for prescribing is the active substance in tablet form. In the absence of contraindications and difficulty in swallowing, tablets become the main way to treat identified diseases. Injections using a solution of Picamilon are advisable in severe cases when the patient is unable to take the medicine in the form of tablets.

Dosage in injections

Picamilon injections according to the instructions for use can be carried out through a vein or intramuscularly, based on the patient's condition and the severity of the disease.

In preparation for the introduction of the drug through a dropper, the solution from one ampoule should be diluted in saline with a volume of 200 ml. At an increased dose, a similar proportion is used - 1 ampoule and 200 ml of saline. Administration by intramuscular route does not require dilution of the drug. The volume of liquid can be taken full, i.e. 2 ml or reduce the amount taken by half as directed by a physician.

In a situation of existing circulatory disorders in the brain in a chronic or acute form, the drug solution is administered in an amount of 100-200 mg daily 2 times. In this case, it is recommended to use a combined technique in one of two options:

morning procedure with a dropper, and evening - by injection;
during the first 10 days of treatment, intravenous injections are carried out, and in the following days - intramuscular injections.

Important. The course of therapy lasts for 14-30 days. When determining the timing of treatment, the progress of recovery is taken into account.

In the case of neurosis and asthenia, which were caused by the action of various ailments, intramuscular injections of Picamilon should be carried out at a 10% concentration with a daily dosage of 200-400 mg of the active substance. The duration of therapy is 1 month. If a course is chosen for the treatment of asthenia, then the same drug in tablets is additionally prescribed.

In the process of getting rid of chronic alcoholism, it is necessary to eliminate the hangover syndrome. Then a three-week course of treatment is prescribed with intramuscular injections of a 5% solution with a daily volume of 2-6 ml. If the patient does not have a hangover, then the dose is reduced to 0.8–1.2 ml at the indicated concentration. The duration of therapy is up to 5 weeks with one-time procedures during the day.

Therapy for diseases of the cerebrovascular type is performed by injection into a vein or intramuscularly, 20-50 mg of a 5% solution twice or thrice daily. The course lasts from 1 to 2 months. Therapy of depressive disorders is made by injections for 2-3 months. two or three times a day. A dose of 40-200 mg of liquid at a 5% concentration is used.

To activate the abilities of athletes in order to stimulate mental and physical activity in others, it is recommended that no more than 60-80 mg per day be prescribed for 60 days.

Alcohol poisoning

Acute alcohol poisoning requires intravenous exposure with the appointment of a saturated dosage. The calculation is made individually depending on the patient's condition and taking into account body weight.

For every 1 kg of mass, a dosage of 5 milligrams of the active ingredient is set. Based on this, the volume of the agent in ml is determined, which is extracted from the ampoules. Picamilon is administered once, and then injections are given into a vein through a dropper at a dosage of 1.56 mg per 1 kg of body weight for 1 hour.

A certain amount of the substance is diluted in saline. Reception is made in the morning for a four-hour period, and then repeated in the evening.

Dosages for younger patients

In the process of treating diseases in children under the age of 3, as mentioned earlier, it is not recommended to use injections. For this purpose, dosages in tablets of 20 mg are provided. The medicine is used without chewing - the child should swallow it whole and drink it with plenty of water. The course of therapy is 1-1.5 months. with a possible recurrence at intervals of at least 3 months.

When administered to children with urinary problems, the dosage is:

from 3 to 10 years - 1 tab. 20 mg three times a day;
from 11 to 15 years - 1 tab. 50 mg twice in 24 hours;
older than 15 years - 50 mg three times a day.

In the case of treatment of other diseases, children aged 3-10 years old take 1 table. 50 mg twice a day, and over 10 years old - 20 mg 3 times daily.

Overdose

Information on emergency cases of overdose has not been identified. However, taking excessively high doses can cause an increase in side effects.

Side effects

In general, Picamilon is normally tolerated by patients, however, in some situations, individual negative manifestations are possible in the form of allergic reactions - skin rashes and itching on the surface of the skin. Dizziness, nausea, vomiting are also possible.

Sometimes, instead of reducing the symptoms of mental disorders, their exacerbation is observed in the form of increased anxiety, irritability. There are known cases of increased excitement and the appearance of unreasonable fears. These manifestations may be accompanied by a flush of blood to the face, redness, and when injected into a vein - the effect of "goosebumps".

If there are negative effects, you should report them to your doctor. Then it may be necessary to reduce the dose or switch to other drugs.

Current analogues

Among the options close in action to Picamilon, we can distinguish PikogaM, Amilonosar, and Picanoil. If necessary, it is possible to replace such drugs as Piracetam, Phezam, Ceraxon, Cerebrolysin, Pantocalcin, Aminalon, Lucetam, Neurovin, and some others.

Picamilon (tablets, solution) - instructions for use, analogues, reviews, price

Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Picamilon is an nootropic drug, which have a stimulating effect on the higher functions of the brain. This means that nootropics, including Picamilon, improve the ability to mental work, increase brain endurance in relation to intellectual stress, and also increase the resistance of nervous tissue to the negative effects of damaging factors, such as hypoxia, etc. In addition, Picamilon reduces the severity neurological disorders. Therefore, Picamilon is used to treat various diseases associated with damage to brain structures, to improve mental abilities, as well as in the complex treatment of conditions associated with anxiety or fear.

Composition, dosage forms and names of Picamilon

Picamilon is currently available in two dosage forms:

Tablets for oral administration;
Injection (for intramuscular or intravenous administration).

Tablets are available in two dosages - 0.02 g (20 mg) and 0.05 g (50 mg) of the active substance. The solution for injection is available in sealed ampoules also in two concentrations of the active ingredient - 50 mg / ml (5%) and 100 mg / ml (10%). In everyday speech, the short names "Pikamilon tablets" or "Pikamilon ampoules" are used to refer to various dosage forms of the drug. To indicate the dosage of tablets, the short name "Pikamilon 0.02" or "Pikamilon 0.05" is often used, where the number indicates the amount of active substance in the preparation. To distinguish the dosages of the solution, other everyday names are used, such as "Pikamilon 50" or "Pikamilon 100". Thus, the well-established names of the drug ("Pikamilon 0.02", "Pikamilon 0.05", "Pikamilon 50" and "Pikamilon 100") are convenient and allow you to quickly and reliably distinguish between different dosage forms and their dosages.

As an active substance, tablets and solution for injection contain Picamilon nicotinoyl-gamma-aminobutyric acid (nicotinoyl-GABA) in various dosages:

Tablets - 0.02 g or 0.05 g each, which corresponds to 20 mg and 50 mg;
Solution for injection - 50 mg / ml or 100 mg / ml, which corresponds to 5% or 10% concentration.

Picamilon tablets of both dosages contain the following components as excipients:

Potato starch;
Magnesium hydroxycarbonate hydrate;
Sucrose;
calcium stearate;
Stearic acid;
Talc.

Picamilon solution does not contain any excipients.

Picamilon tablets have the shape of a cylinder, flattened on both sides, each of which has a chamfer. Tablets of both dosages are colored white or white with a creamy tint. Ampoules contain 2 ml of a clear solution of 5% or 10% concentration. Tablets are available in packs of 30, 50 or 100 pieces, and the solution - 10 ampoules.

Picamilon - manufacturer

In the list of manufacturers of Picamilon indicated on the package or leaflet with instructions for use, the following companies may be listed:

Akrikhin Chemical-Pharmaceutical Plant OJSC (Russia);
CJSC NPK Echo (Russia).

JSC Akrikhin is the owner of the registration certificate for the drug, that is, it owns the legal rights to the production technology of Picamilon, which, of course, is a trade secret. However, by agreement, the marketing authorization holder can transfer the drug manufacturing technology to another company, which acts as a kind of contractor, performing work on its production and packaging. It is in the role of such a contractor that ZAO NPK Echo acts, at whose production facilities Picamilon tablets and solution are produced. That is, the direct manufacturer is the Echo plant, and the legally responsible person to whom all claims regarding the quality of the drug must be directed is Akrikhin OJSC. However, from a legal point of view, the manufacturer of Picamilon should be considered the owner of the registration certificate, that is, Akrikhin, a chemical and pharmaceutical plant.

Picamilon - photo

Scope and therapeutic effect

The scope and therapeutic effect of Picamilon are due to its active substance, nicotinoyl-GABA. This substance is a stimulant of metabolism in nerve cells, of which the brain actually consists. In addition, nicotinoyl-GABA has an antihypoxic and antioxidant effect on brain tissues and cells, thereby protecting it from various damages.

The antihypoxic effect of Picamilon is to improve the blood supply to the brain, which is especially important for atherosclerosis, thrombosis or vascular disease, when tissues receive an insufficient amount of blood, and, consequently, oxygen and nutrients. Picamilon improves the blood supply to the brain, which allows oxygen and nutrients to be delivered to all structures.

In addition, Picamilon improves eye microcirculation and blood supply to all internal organs. Improvement of microcirculation is achieved due to the antiaggregatory action of Picamilon, which consists in the prevention of agglutination and adhesion of platelets with the formation of blood clots.

The antioxidant effect of Picamilon is to increase the resistance of cells to the negative effects of various free radicals, which are toxic molecules that can damage the membrane structure and cause cell death. Under the influence of Picamilon, brain cells successfully resist the negative effects of free radicals, remain structurally intact and functionally complete. This improves the functional activity of the brain, which, in turn, significantly enhances cognitive abilities (thinking, memory, attention, etc.).

In addition, nicotinoyl-GABA has a moderate tranquilizing effect (normalizes mood, reduces aggression, relieves fears, anxiety, etc.), not accompanied by the effect of drowsiness and muscle relaxation (relaxation of all muscles). Picamilon also has a psychostimulating effect, restoring physical and intellectual performance during high loads or overwork.

Separately, it is worth noting the ability of Picamilon to neutralize the inhibitory effect of alcohol on the central nervous system.

Given the therapeutic effect of Picamilon, the drug is used for disorders of cerebral circulation associated with hypoxia or stroke, as well as for cerebrovascular insufficiency, dyscirculatory encephalopathy, craniocerebral trauma, migraines or alcohol brain damage.

When using Picamilon in regular courses, a person improves intellectual and physical performance and memory, normalizes sleep, and also reduces or completely disappears anxiety. Motor and speech disorders, provoked by neurological disorders, decrease or disappear against the background of the course use of Picamilon.

Indications for the use of Picamilon

Picamilon in tablets and solution for injection is indicated for use in the presence of the following conditions or diseases:
1. Acute ischemic cerebrovascular accident (ischemic stroke) of mild or moderate severity;
2. Recovery period after an ischemic stroke;
3. Subacute ischemic stroke;
4. Cerebrovascular insufficiency (insufficiency of cerebral circulation);
5. Encephalopathy;
6. Vegetative-vascular dystonia;
7. Traumatic brain injury;
8. Neuroinfections (for example, tick-borne encephalitis, neurosyphilis, etc.);
9. States of anxiety, fear, irritability, depression and emotional lability (mood swings);
10. Depression in the elderly;
11. Senile (senile) psychoses;
12. Asthenic conditions provoked by neuropsychiatric diseases or excessive mental or physical stress;
13. Recovery period after suffering various diseases;
14. Chronic alcoholism (in order to reduce asthenia, neurotic, psychotic and recurrent conditions);
15. Alcoholic encephalopathy;
16. Complex therapy of acute alcohol intoxication ("delirious tremens");
17. Prevention and relief of migraine;
18. Primary open-angle glaucoma with normal intraocular pressure;
19. Diseases of the retina and optic nerve;
20. Urination disorders in children and adults (in order to adapt the properties and functions of the bladder);
21. Improving the tolerance of intense intellectual and physical stress (for example, in people working in a tense rhythm, extreme conditions, etc.);
22. Recovery of working capacity in athletes or after heavy mental or physical work.

Instructions for use

It has been established that Picamilon in the form of tablets is preferable for use in various diseases. Therefore, it is recommended to always use Picamilon tablets if a person can swallow them and tolerate oral administration of the drug normally. Picamilon in solution for injection is used only in the treatment of acute conditions when a person is not able to take pills. Consider the rules for the use, dosage and duration of treatment with Picamilon tablets and injections.

Picamilon injections - instructions for use

For intravenous infusion administration of the drug ("dropper"), the contents of one ampoule are diluted in 200 ml of sterile saline. If it is necessary to inject more than 1 ampoule of the drug, then the amount of saline that is necessary for dilution is calculated based on the following ratio: 1 ampoule of Picamilon 5% or 10% concentration per 200 ml of saline.

For intramuscular or intravenous jet administration, Picamilon solution is used immediately after opening the ampoule, without performing any additional actions. Intramuscularly and intravenously, you can enter the entire volume of the solution from one ampoule (2 ml) or half (1 ml).

For the treatment of acute or chronic cerebrovascular accident, Picamilon is administered 100-200 mg (2 ml of a 5% solution - 2 ml of a 10% solution) 2 times a day, with a "dropper" in the morning and an intramuscular injection in the evening. It is possible to administer Picamilon intravenously for the first 10 days, and intramuscularly for the next decade. The duration of the course of therapy is from 2 to 4 weeks, depending on the speed of recovery.

In addition, Picamilon is effective in maintaining the mental and physical performance of the child during periods of particularly intense stress at school. Also, the drug is indicated for use during the rehabilitation period after various traumatic brain injuries. In young children under 3 years of age, Picamilon in combination with magnesium and B vitamins is used to eliminate increased nervous excitability, to improve sleep and stop constant crying, tantrums and bad mood.

However, in addition to these applications, Picamilon is now often prescribed to children under three years of age in order to maintain muscle tone and to improve overall development. Such use of Picamilon is unreasonable, ineffective and harmful, since the drug will not be able to improve the development of the child and make him a "genius", but it will completely disrupt the process of intensive brain formation that occurs during this particular period. Remember that Picamilon is a medicine and should only be taken when indicated and not for "prophylaxis". Any useful and effective medicine, used off-label, can lead to severe negative consequences.

Picamilon for children - instructions for use

For children, you should use tablets with a dosage of 20 mg (0.02 g), which is conventionally considered "children's". The tablet is given to the child and asked to swallow it without chewing, but simply with half a glass of clean water. If the child wants to take the pill with any other liquid (for example, juice, milk, compote, etc.), then let him do it, since eating and drinking does not affect the absorption of Picamilon. Therefore, tablets can be taken regardless of the meal.

The duration of the course of using Picamilon in children with various conditions and diseases is the same and ranges from 1 to 1.5 months. If necessary, courses of therapy can be repeated, observing intervals between them lasting at least 3-5 months.

The dosage and frequency of taking Picamilon for the treatment of any diseases, with the exception of urination disorders, is determined by the age of the child:

Children 3 - 10 years old - take 20 mg (1 tablet) twice a day;
Children over 10 years old - take 20 mg (1 tablet) three times a day.

The dosage of Picamilon for the treatment of urinary disorders is as follows:

Children 3 - 10 years - 20 mg (1 tablet) three times a day;
Children 11-15 years old - 50 mg (1 tablet) twice a day;
Adolescents over 15 years of age and adults - 50 mg three times a day.

Side effects

Picamilon is generally well tolerated and rarely causes side effects. Even if a side effect develops, as a rule, it has a low or moderate severity.

Side effects of Picamilon include the following symptoms:

Breastfeeding period.

Picamilon - analogues

Currently, there are analogues and synonyms of Picamilon on the domestic pharmaceutical market. Analogues include drugs that have a similar therapeutic effect, but contain a different active substance. Synonyms include drugs containing the same active substance as Picamilon.

Synonyms of Picamilon are the following drugs:

Amilonosar solution and tablets;
Sodium salt of N-nicotinoyl gamma-aminobutyric acid;
Picanoyl tablets;
Picogam tablets.

The following drugs are analogues of Picamilon:
1. Acefen tablets;
2. Bravinton concentrate;
3. Vero-Vinpocetine tablets;
4. Vinpotropil capsules and solution;
5. Vinpocetine tablets and concentrate;
6. Vinpocetine forte tablets;
7. Vincetin tablets;
8. Glycine and Glycine forte tablets;
9. Gopantam tablets;
10. Demanol solution;
11. Idebenone capsules and tablets;
12. Cavinton tablets and concentrate;
13. Cavinton forte;
14. Calcium hopantenate tablets;
15. Carnitetin capsules;
16. Cogitum solution;
17. Combitropil capsules;
18. Korsavin and Korsavin forte tablets;
19. Cortexin lyophilizate and dry extract;
20. Lucetam tablets and solution;
21. Memotropil tablets;
22. minisem drops;
23. Neuromet capsules;
24. Noben capsules;
25. NooKam capsules;
26. Nooklerin solution;
27. noopept tablets;
28. Nootropil capsules, tablets and solution;
29. Omaron tablets;
30. Pantogam syrup and tablets;
31. pantocalcin tablets;
32. Piracesin capsules;
33. Piracetam granules, capsules and solution;
34. Pyriditol tablets;
35. Telektol tablets;
36. Thiocetam tablets and solution;
37. Phezam capsules;
38. Phenotropil tablets;
39. Celestab capsules;
40. Cellex solution;
41. Ceraxon solution;
42. Cerebrolysate solution;
43. Cerebrolysin solution;
44. Encephabol tablets and suspension;
45. epithalamin powder;
46. Escotropil solution.

Picamilon - reviews

The vast majority of reviews about Picamilon are positive, which is associated with a pronounced clinical effect of the drug, which is well felt by people. So, the reviews indicate that Picamilon perfectly helps to cope with increased mental stress, improving the assimilation of the material and making the thought clear and precise, and also calms, relieves anxiety, relieves fear and normalizes sleep. The ability of Picamilon to normalize sleep is noted by many people who took the drug for various diseases associated with cerebrovascular disorders (for example, after suffering meningitis, with cervical osteochondrosis, etc.).

Separately, it is worth noting that, according to reviews, Picamilon effectively stops a migraine attack and prevents their development. For people suffering from migraines, according to their own reviews, Picamilon is literally a lifesaver.

The undoubted advantages of Picamilon include its low cost, which allows people to regularly undergo preventive and therapeutic courses of taking the drug.

There are literally a few negative reviews about Picamilon, and they are not due to its inefficiency, but to the development of side effects, against which people had to stop taking the medicine.

Picamilon is a nootropic drug that corrects various types of circulatory disorders in the brain.

It has antiaggregatory, psychostimulating, antioxidant and tranquilizing therapeutic effects. Picamilon helps with migraines, helps to normalize sleep and cerebral circulation. In addition, the drug increases the level of efficiency, eliminates anxiety and causeless fear.

This drug was synthesized in 1969 at the All-Union Vitamin Research Institute, and it has been used in medicine since 1986. The active substance is nicotinoyl gamma-aminobutyric acid.

Clinical and pharmacological group

Nootropic agent, dilates the vessels of the brain.

Terms of dispensing from pharmacies

Released without a doctor's prescription.

Prices

How much does Picamilon cost in pharmacies? The average price is at the level of 150 rubles.

Release form and composition

Picamilon is available in the form of tablets for oral administration of 30 pieces in a carton pack in blisters of 10 pieces with a detailed description attached.

The active substance is N-nicotinoyl-gamma-aminobutyric acid sodium salt, its content in various dosage forms of the drug:

1 ml solution for intravenous and intramuscular administration - 50 or 100 mg;
1 tablet - 20 or 50 mg.

Auxiliary components of tablets: potato starch, magnesium hydroxycarbonate hydrate, talc, sucrose, stearic acid or calcium stearate.

Pharmacological effect

The drug has a pronounced psychostimulating, antiplatelet, tranquilizing and antioxidant effect. The use of Picamilon helps to normalize tissue metabolism, while activating the functioning of the brain. The agent stimulates the blood circulation of the brain by reducing vascular resistance, suppressing platelet aggregation, improving microcirculation and increasing the rate of cerebral blood flow.

With a course application, this drug activates the physical and mental performance of the body, helps to improve memory, reduce headaches and normalize sleep. When using Picamilon, the feeling of anxiety, tension and fear is minimized or completely disappears, and the condition of patients with motor and speech disorders improves significantly.

The low toxicity of the drug and the effectiveness of small dosages make it possible to use it in gerontology and pediatric practice. Does not have embryotoxic, carcinogenic and teratogenic effects. It has no contraindications during the lactation period. This drug is not addictive.

Indications for use

This medication is prescribed for the treatment of many diseases and pathologies, including such phenomena as:

diseases of the central nervous system;
depressive disorders;
ischemic circulatory disorders of the brain;
open-angle;
cerebrovascular insufficiency in old age;
consequences of traumatic brain injuries and neuroinfections;
recovery period after;
some diseases of the retina and optic nerve;
acoustic neuritis;
asthenic conditions, accompanied by fear, anxiety and emotional instability;
- a set of disorders, which are based on violations of the regulation of the tone of the autonomic nervous system.

Also, this medicine is used as part of complex therapy for the treatment of neuroinfections, the prevention and relief of migraines, for the patient's condition with alcohol intoxication. It is often prescribed in urology to normalize the adaptive activity of the bladder in patients with urination disorders. Increases a person's resistance to mental and physical stress, helping to cope with extreme situations, quickly restore physical performance.

Contraindications

Picamilon is contraindicated for use in the presence of the following diseases or conditions in a person:

Acute kidney disease
Chronic renal failure;
Hypersensitivity to the components of the drug;
Pregnancy;
breastfeeding period.

According to the instructions, Picamilon is prohibited for use in the treatment of children under the age of 3 years.

Use during pregnancy and lactation

The drug is not prescribed for the treatment of cerebrovascular accidents in pregnant women and nursing mothers, since there is no clinical experience and the safety of the drug has not been established.

If necessary, therapy of a nursing mother should stop lactation.

Dosage and method of application

The instructions for use indicate that Picamilon tablets are taken orally, regardless of the meal.

Asthenia, psychosis: 40-80 mg per day for 1-1.5 months. In some cases, the daily dose may be increased to 200-300 mg;
Depressive conditions in elderly patients: depending on the clinical situation, 40-200 mg per day (optimally - 60-120 mg) in 2-3 doses for a course of 1.5-3 months;
Restoring working capacity and increasing the body's resistance to stress: 60-80 mg per day for 1-1.5 months. Athletes are recommended to take Picamilon during the training period (2 weeks);
Cerebrovascular diseases: 20-50 mg 2-3 times a day (but not more than 150 mg per day) for a 1-2-month course. After 5-6 months, a second course is prescribed;
Alcoholism: during the withdrawal period - 100-150 mg per day for 6-7 days, with persistent disorders outside of withdrawal - 40-60 mg per day for 4-5 weeks.

Solution for intravenous and intramuscular administration

Standard regimens for the use of the drug:

Asthenic conditions: 20-40 mg per day / m for a 1-month course (at the same time, Picamilon is prescribed in tablets);
Relief of acute uncomplicated intoxication with ethanol (as part of combination therapy): at the beginning of treatment - at a loading dose of 5 mg / kg, then at a maintenance dose - 1.56 mg / kg / hour in 2.5 liters of infusion solution for 4 hours , frequency of use - 2 times a day (morning and evening);
Chronic disorders of cerebral circulation: 100-200 mg 1 or 2 times a day. Based on the patient's condition, the doctor applies one of the following schemes: injects the drug first in / in for 10 days, then - in / m; or throughout the course in the morning - in / in the drip, in the evening - in / m. The duration of treatment is from 15 to 30 days.

Side effects

Picamilon can cause anxiety, headaches, nervous excitement and other negative symptoms from the nervous system. The medicine can also cause nausea or an allergic reaction.

Overdose

An overdose of Picamilon is manifested by an increase in the severity or the appearance of side effects.

special instructions

To obtain the maximum therapeutic effect, it is necessary to take drugs from the nootropic group strictly according to the doctor's prescription. It is strictly forbidden to adjust the prescribed dose of the drug without consulting a doctor.

With the rapid introduction of the drug, dizziness, a feeling of heat in the body may appear. It is better to take the drug at the same time. At the first sign of adverse reactions, you need to stop taking the medication, seek medical help. Compliance with simple rules will help increase the effect of treatment, achieve a good prognosis for recovery.

drug interaction

Picamilon reduces the duration of action of drugs from the barbiturate group (for example, Phenobarbital, Barbamil, etc.) and enhances the effects of narcotic analgesics.

The human brain, the main element of the central nervous system, is the most complex device, without the normal operation of which the body is not able to function normally. The most mysterious and functional organ of the human body should be given special attention and care.

In modern pharmaceuticals, there are many drugs created for the regeneration of brain cells and their restoration. These are nootropic drugs, one of which is Picamilon. But, before using this remedy, you should figure out why Picamilon is prescribed and get acquainted with its side effects.

Picamilon is a Russian-made nootropic drug

Such a nootropic refers to monocomponent, that is, consisting of one active component: nicotinoyl gamma-aminobutyric acid. When manufacturing, a number of necessary auxiliary elements are added to the medication:

talc;
starch;
calcium stearate.

Nicotinoyl gamma-aminobutyric acid (NICOTINOYL GAMMA-AMINOBUTYRIC ACID) is a crystalline white powder. This component is hygroscopic and highly soluble in water.

NGAK refers to a number of nootropics that improve metabolism (metabolism) of the brain and belongs to a number of multivitamins.

The dosage of the tablet is 20 or 50 mg. In the form of an injection solution, the substance is dosed at the rate of 100 mg per milliliter.

What is the medicine for?

To understand what Picamilon tablets are for and how they help patients, you need to consider the effects that the medicine has. Its main effect is the expansion / restoration of blood vessels and the activation of the stimulatory parts of the brain.. This drug actively affects the higher mental brain functions.

Picamilon has been successfully used to treat alcohol withdrawal.

According to the results of studies conducted by WHO (World Health Organization), nootropic drugs act on a person as follows:

Regulate memory processes.
Restore the ability to perceive new information.
Increase the resistance of the central nervous system to the negative influence of external factors.

Features of the drug

Picamilon (unlike a number of other medicines) does not cause persistent dependence of the body and does not provoke the development of weakness. The physical capabilities of a person remain at the same level, they are not depleted. The action of the drug occurs due to the improvement of metabolic processes and a direct effect on the vessels of the brain.

Indications for the use of the drug

To understand what Picamilon medicine is for, it is necessary to study the effects that this remedy has on a person. Here is their complete list:

Psychostimulation. It helps to mentally prepare a person for any necessary action. There is a kind of “toning” of the nervous system.
Anti-asthenic effect. Removes severe weakness, lethargy, removes fatigue and increased exhaustion. Such symptoms are characteristic of people with various pathologies.
Antidepressant effect. Relief of states of anxiety, inexplicable fear, various depressive manifestations.
adaptogenic effect. Increasing the body's strength to the manifestations of numerous negative external stimuli (environmental pollution, work in hazardous industries, passive smoking).
Vasovegetative effect. Restoring the regulation of vegetative processes: improving metabolism, increasing tissue excitability. The tool normalizes the activity of internal resources and behavioral reactions.
Light sedative effect. The drug has a mild sedative effect in neurosis-like conditions.

Picamilon also works to increase the clarity of human thinking, improves learning processes, concentrating the ability to memorize new information. Revitalizes speech functions and parts of the brain responsible for memory.

When is Picamilon prescribed?

What Picamilon helps from is the main and urgent question that confronts a person when a doctor recommends this drug to him. Nootropics work by stimulating and activating the metabolic processes of the cellular tissue of the brain. Due to this, the drug significantly helps in the fight against the following problems (diagnosed pathologies or conditions):

asthenic syndrome;
vegetovascular dystonia;
open-angle glaucoma;
depressive states characteristic of the elderly;
problems with the blood circulation of the brain of moderate / mild degree;
in order to restore physical condition after heavy sports competitions;
in the complex treatment of chronic alcoholism and alcohol intoxication of any type;
as an adjuvant in the treatment of migraine (Pikamilon is used for preventive purposes);
to relieve excessive physical stress of persons involved in hard work, experiencing psychological tension due to the specifics of the work;
cerebrovascular insufficiency (when small areas of degradation appear in the brain, the development of which occurs due to circulatory disorders).

Picamilon and alcohol intoxication

This original Russian-made drug is successfully used in the treatment of alcohol intoxication of varying severity. With a hangover syndrome, Picamilon effectively relieves headaches, removes anxiety, quickly restoring sleep and performance.

Pharmacological action of the drug

At the same time, the agent blocks the destructive effect of ethyl alcohol on the human body, in particular on the central nervous system. But it does not cause addiction and drowsiness.

Also, the drug is actively used by doctors when removing patients from a deep, prolonged binge. But you should know that this medicine only works to reduce the negative effects of ethyl alcohol on the functionality of the body. But he is unable to solve the problem of edema and impaired redistribution of fluid associated with intoxication.

How to take the drug correctly

Picamilon produces in several forms. The correct use of the drug and the recommended dose depend on this. Before using the medication, you must carefully study the attached instructions.

Please read the instructions carefully before using the product.

How to take Picamilon tablets

The tablet preparation should be taken orally in whole pills (it is not recommended to grind and dissolve them in a liquid). Wash down the tablets with plenty of purified water (from 100-150 ml).

Picamilon tablets are allowed to be consumed regardless of the meal, at any time convenient for a person.

The dosage of Picamilon and the duration of the course of use depend on each specific case and the diagnosed problem:

Diagnosis	The amount of the drug	Duration of admission
circulatory problems (hypertension)	1 tablet three times daily	1-2 months (the course is repeated every six months)
migraine attacks	1 tablet (50 mg) three times daily	only when you feel an impending attack
with increased physical / mental stress	2-10 pieces of dragee twice a day	depends on the degree of load and age (strong athletes recommend up to 200 mg daily)
therapy for glaucoma	3 tablets daily	30-35 days
pathology of the urinary system	one tablet three times daily	one month

How to take Picamilon tablets, the instruction of which says that the drug helps to get a person out of a hangover? To relieve intoxication caused by excessive drinking, the drug is used at the rate of a daily dose of 150-200 mg for a whole hangover day. The number of dragees depends on the form of release of the drug: 10, 20, 30 or 50 mg.

The use of the drug in injections

Picamilon in an injection form is used only in difficult cases, with serious and severe neurosis-like conditions or severe cerebrovascular accident. A concentrated agent is administered intramuscularly or intravenously (jet or infusion injections).

What do Picamilon ampoules look like?

Also, the tool is used by drip injection. For droppers, the ampoule of the drug is diluted with saline (200 ml). Dose the drug, focusing on the age of the patient:

children 100 mg / day;
adults - 200 mg / day.

In some cases, the daily dose of the drug can be divided into a couple of doses. The duration of the course of treatment in injectable form is about 1.5-2 weeks.

Beware, danger!

This medication has a minimum of side effects and is almost always well tolerated by all patients. It can even be given to children. But, like any drug, Picamilon has some conditions under which its intake is limited.

Side effects

nausea;
the appearance of a headache;
slight dizziness;
redness of the skin;
allergic rash such as urticaria;
increased anxiety, irritability;
with intravenous use, a feeling was noted that "goosebumps run."

Side effects with Picamilon are very rare.

As a rule, such negative consequences are expressed so weakly that they do not affect the quality of life in any way.. But, if side effects cause inconvenience, doctors lower the dosage of the drug or replace it.

Contraindications

Picamilon also has a number of contraindications to its appointment. There are a number of patients who should forget about taking the medicine because of the following contraindications they have:

Chronic renal pathologies.
The period of pregnancy and breastfeeding.
Excessive sensitivity to the constituent components of the remedy.

With extreme caution, you should use the remedy in case of a severe stage of cerebral circulatory disorders. You should also know and remember that Picamilon enhances the medicinal effect of analgesics (if they contain narcotic components). But the effect of barbiturates, on the contrary, lowers.

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